Rabbit Polyclonal Antibody to Claudin 1

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

400-880-2824

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:Claudin-10; OSP-like protein; CLDN10;
应用:WB
反应种属:Human,Mouse
规格：50μl/100μl

Description
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. May form permselective paracellular pores; isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. Plays a key role in controlling cation selectivity and transport in the thick ascending limb (TAL) of Henle’s loop in kidney.Siu Tim Cheung, Clin. Cancer Res., Jan 2005; 11: 551 – 556.Hiroki Fujita, J. Histochem. Cytochem., Aug 2006; 54: 933 – 944.Christina M. Van Itallie, Am J Physiol Renal Physiol, Dec 2006; 291: F1288 – F1299.Anne Florin, Endocrinology, Mar 2005; 146: 153

Description

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. May form permselective paracellular pores; isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. Plays a key role in controlling cation selectivity and transport in the thick ascending limb (TAL) of Henle’s loop in kidney.Siu Tim Cheung, Clin. Cancer Res., Jan 2005; 11: 551 – 556.Hiroki Fujita, J. Histochem. Cytochem., Aug 2006; 54: 933 – 944.Christina M. Van Itallie, Am J Physiol Renal Physiol, Dec 2006; 291: F1288 – F1299.Anne Florin, Endocrinology, Mar 2005; 146: 153

Specification
Aliases	Claudin-10; OSP-like protein; CLDN10;
Entrez GeneID	9071;
Swissprot	P78369
WB Predicted band size	25kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from human Claudin 10.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000

	Western blot analysis of extracts from LOVO cells, using Claudin 10 antibody P41790.
	Western blot analysis of extracts from A549 cells (Lane 2), using Claudin 10 antiobdy P41790. The lane on the left is treated with synthesized peptide.