中文 
别名:CLD3; CLDN3; HRVP1; CPE-R 2; CPE-receptor 2应用:WB
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Peacock R.E., Genomics 46:443-449(1997)Katahira J., J. Biol. Chem. 272:26652-26658(1997)The MGC Project Team; Genome Res. 14:2121-2127(2004) |
| Specification | |
|---|---|
| Aliases | CLD3; CLDN3; HRVP1; CPE-R 2; CPE-receptor 2 |
| Entrez GeneID | 1365; |
| Swissprot | O15551 |
| WB Predicted band size | 28kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 219 (R-K-D-Y(p)-V) derived from Human Claudin 3. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
 |
Western blot analysis of extracts from COLO cells treated with EGF using Claudin 3 (Phospho-Tyr219) Antibody P40491.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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