Rabbit Polyclonal Antibody to CLDN22

包装: 1G|100G|500G|1KG|100KG

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别名:Claudin-22, CLDN22
应用:WB,FCM
反应种属:Human, Mouse
规格：50μl/100μl

Description
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3′ UTR of the WWC2 gene (GeneID: 80014) on the opposite strand.

Description

This gene encodes a member of the claudin family. Claudins
are integral membrane proteins and components of tight junction
strands. Tight junction strands serve as a physical barrier to
prevent solutes and water from passing freely through the
paracellular space between epithelial or endothelial cell sheets,
and also play critical roles in maintaining cell polarity and
signal transductions. This gene is intronless and overlaps the 3′
UTR of the WWC2 gene (GeneID: 80014) on the opposite strand.

Specification
Aliases	Claudin-22, CLDN22
Entrez GeneID	53842
Swissprot	Q8N7P3
WB Predicted band size	24.5kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	This CLDN22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-117 amino acids of human CLDN22.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
FCM	1/10-1/50

	CLDN22 Antibody (Center) (Cat. #P30746) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CLDN22 antibody detected the CLDN22 protein (arrow).
	CLDN22 Antibody (Center) (Cat. #P30746) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the CLDN22 antibody detected the CLDN22 protein (arrow).
	CLDN22 Antibody (Center) (Cat. #P30746) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.