别名:CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1应用:WB
反应种属:Human,Mouse
规格:50μl/100μl
| Description |
|---|
| Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. |
| Specification | |
|---|---|
| Aliases | CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1 |
| Entrez GeneID | 836 |
| Swissprot | P42574 |
| WB Predicted band size | Calculated MW: 32 kDa; Observed MW: 35 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Purified recombinant human Caspase-3 protein fragments expressed in E.coli. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
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Western blot analysis of Cleaved-Caspase3 in Jurkat and 3T3 lysates using Cleaved-Caspase3 p17 antibody. |
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Western blot analysis of Cleaved-Caspase 3 p17 in Jurkat cells, untreated or treated with Staurosporine (1 μM; 3 hr), using Cleaved-Caspase3 p17 antibody (upper) or βActin (8F10) antibody(lower). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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