Rabbit Polyclonal Antibody to CLK4

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

400-880-2824

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:Dual specificity protein kinase CLK4; EC 2.7.12.1; CDC-like kinase 4; CLK4;
应用:WB
反应种属:Human,Mouse
规格：50μl/100μl

Description
Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.Schultz J., Genomics 71:368-370(2001).McNally T., Protein Sci. 12:1562-1566(2003).Kantham L., Biochem. Biophys. Res. Commun. 304:125-129(2003).

Description

Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.Schultz J., Genomics 71:368-370(2001).McNally T., Protein Sci. 12:1562-1566(2003).Kantham L., Biochem. Biophys. Res. Commun. 304:125-129(2003).

Specification
Aliases	Dual specificity protein kinase CLK4; EC 2.7.12.1; CDC-like kinase 4; CLK4;
Entrez GeneID	57396;
Swissprot	Q9HAZ1
WB Predicted band size	65kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from internal of human CLK4.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.