Rabbit Polyclonal Antibody to CLK4

包装: 1G|100G|500G|1KG|100KG

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别名:
应用:IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.

Description

The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.

Specification
Swissprot	Q9HAZ1
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human CLK4
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/150-1/300
ELISA	1/5000-1/10000

	The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P09523(CLK4 Antibody) at dilution 1/170. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P09523(CLK4 Antibody) at dilution 1/170. (Original magnification: ×200)