Rabbit Polyclonal Antibody to CLPTM1L

包装: 1G|100G|500G|1KG|100KG

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别名:CRR9
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Cleft lip and palate transmembrane protein 1-like protein (CLPTM1-like protein), also known as cisplatin resistance-related protein 9 (CRR9p), is a protein that in humans is encoded by the CLPTM1L gene. CRR9p is associated with cisplatin-induced apoptosis. CLPTM1L, which lies within a cancer susceptibility locus on chromosome 5 (5p15.33), has been found to be commonly over-expressed in lung tumors and to confer resistance to apoptosis caused by genotoxic agents in association with up-regulation of the anti-apoptotic protein, Bcl-xL.

Description

Cleft lip and palate transmembrane protein 1-like protein (CLPTM1-like protein), also known as cisplatin resistance-related protein 9 (CRR9p), is a protein that in humans is encoded by the CLPTM1L gene. CRR9p is associated with cisplatin-induced apoptosis. CLPTM1L, which lies within a cancer susceptibility locus on chromosome 5 (5p15.33), has been found to be commonly over-expressed in lung tumors and to confer resistance to apoptosis caused by genotoxic agents in association with up-regulation of the anti-apoptotic protein, Bcl-xL.

Specification
Aliases	CRR9
Swissprot	Q96KA5
WB Predicted band size	62 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide of human CLPTM1L
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/200-1/1000
IHC	1/50-1/200
ELISA	1/1000-1/2000

	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: K562 cell, Primary antibody: P04785(CLPTM1L Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
	The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P04785(CLPTM1L Antibody) at dilution 1/60. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P04785(CLPTM1L Antibody) at dilution 1/60. (Original magnification: ×200)