Rabbit Polyclonal Antibody to CMTR2

包装: 1G|100G|500G|1KG|100KG

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别名:AFT; MTr2; HMTr2; FTSJD1
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2′-O-ribose methylation to the 5′-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m7GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m7GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N7 methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs.

Description

S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2′-O-ribose methylation to the 5′-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m7GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m7GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N7 methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs.

Specification
Aliases	AFT; MTr2; HMTr2; FTSJD1
Swissprot	Q8IYT2
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein of human CMTR2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/50-1/200
ELISA	1/5000-1/10000

	The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P03452(CMTR2 Antibody) at dilution 1/69. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P03452(CMTR2 Antibody) at dilution 1/69. (Original magnification: ×200)