Rabbit Polyclonal Antibody to CNBP

包装: 1G|100G|500G|1KG|100KG

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别名:Cellular nucleic acid-binding protein, CNBP, Zinc finger protein 9, CNBP, RNF163, ZNF9
应用:WB,IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Description

This gene encodes a nucleic-acid binding protein with
seven zinc-finger domains. The protein has a preference for binding
single stranded DNA and RNA. The protein functions in
cap-independent translation of ornithine decarboxylase mRNA, and
may also function in sterol-mediated transcriptional regulation. A
CCTG expansion in the first intron of this gene results in myotonic
dystrophy type 2. Multiple transcript variants encoding different
isoforms have been found for this gene.

Specification
Aliases	Cellular nucleic acid-binding protein, CNBP, Zinc finger protein 9, CNBP, RNF163, ZNF9
Entrez GeneID	7555
Swissprot	P62633
WB Predicted band size	19.5kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	This CNBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-118 amino acids from the Central region of human CNBP.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	CNBP Antibody (Center) (Cat. #P32384) western blot analysis in MCF-7 cell line and rat spleen tissue lysates (35ug/lane).This demonstrates the CNBP antibody detected the CNBP protein (arrow).
	Immunohistochemical analysis of paraffin-embedded H. heart section using CNBP Antibody (Center)(Cat#P32384). P32384 was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.