Rabbit Polyclonal Antibody to CNNM3

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别名:ACDP3
应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
The ACDP3 gene, designated CNNM3 by the HUGO Nomenclature Committee, encodes a deduced 707-amino acid protein. Northern blot analysis revealed ubiquitous expression of CNNM3. Immunofluorescence studies showed that all 4 CNMM proteins are predominantly localized in the nucleus. Acdp3 contains 4 transmembrane domains, 2 CBS domains, a DUF21 domain, and a cNMP-binding domain. It also has large alanine- and leucine-rich regions. Northern blot analysis detected variable Acdp3 expression in all mouse tissues examined, with highest expression in brain, kidney, liver, and heart.

Description

The ACDP3 gene, designated CNNM3 by the HUGO Nomenclature Committee, encodes a deduced 707-amino acid protein. Northern blot analysis revealed ubiquitous expression of CNNM3. Immunofluorescence studies showed that all 4 CNMM proteins are predominantly localized in the nucleus. Acdp3 contains 4 transmembrane domains, 2 CBS domains, a DUF21 domain, and a cNMP-binding domain. It also has large alanine- and leucine-rich regions. Northern blot analysis detected variable Acdp3 expression in all mouse tissues examined, with highest expression in brain, kidney, liver, and heart.

Specification
Aliases	ACDP3
Swissprot	Q8NE01
WB Predicted band size	76 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human CNNM3
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/200-1/1000
IHC	1/25-1/100
ELISA	1/1000-1/2000

	Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue, Primary antibody: P00309(CNNM3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
	The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P00309(CNNM3 Antibody) at dilution 1/25. (Original magnification: ×200)