Rabbit Polyclonal Antibody to CNOT7

包装: 1G|100G|500G|1KG|100KG

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别名:CCR4-associated factor 1; CAF-1
应用:WB,IHC,FCM,IP
反应种属:Human,Mouse,Rat,Monkey
规格：50μl/100μl

Description
Has 3′-5′ poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.

Description

Has 3′-5′ poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.

Specification
Aliases	CCR4-associated factor 1; CAF-1
Entrez GeneID	18983
Swissprot	Q60809
WB Predicted band size	Calculated MW: 33 kDa; Observed MW: 33 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat,Monkey
Immunogen	A synthetic peptide of mouse CNOT7
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
IP	1/20
WB	1/500-1/1000
IHC	1/50-1/100
FCM	1/50-1/100

	Western blot analysis of CNOT7 in F9, C6, PC-12, 3T3, Raw264.7 lysates using CNOT7 antibody.
	Western blot analysis of CNOT7 in Molt4, Raji, COS7, Hela lysates using CNOT7 antibody.
	Immunohistochemistry analysis of paraffin-embedded Human lung cancer using CNOT7 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.