中文 
别名:BS BSVD1, COL4A1s, PADMAL, RATOR应用:WB
反应种属:Human,Mouse,Rat
规格：50μl/100μl
| Description |
|---|
| This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
| Specification | |
|---|---|
| Aliases | BS BSVD1, COL4A1s, PADMAL, RATOR |
| Entrez GeneID | 1282 |
| WB Predicted band size | 161kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthesized peptide derived from COL4A1. at AA range: 1428-1443 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3 |
| Application | |
|---|---|
| WB | 1/500-1/2000 |
| ELISA | 1/10000-1/20000 |
 |
Western Blot analysis of Hela MCF-7 U2OS 293T KB 293T VEC cells using COL4A1 Polyclonal Antibody diluted at 1:800. Secondary antibody was diluted at 1:20000 |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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