Rabbit Polyclonal Antibody to COX6B2

包装: 1G|100G|500G|1KG|100KG

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别名:CT59; COXVIB2
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. Localized to the intermembrane space, COX6b2 (Cytochrome c oxidase subunit 6B2), also known as Cytochrome c oxidase subunit VIb isoform 2 and Cancer/testis antigen 59, is a 88 amino acid mitochondrial protein that is responsible for joining the two COX monomers to form the COX dimer. COX6b2 is specifically expressed in testis and is found to be upregulated in certain cancer cell lines.

Description

The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. Localized to the intermembrane space, COX6b2 (Cytochrome c oxidase subunit 6B2), also known as Cytochrome c oxidase subunit VIb isoform 2 and Cancer/testis antigen 59, is a 88 amino acid mitochondrial protein that is responsible for joining the two COX monomers to form the COX dimer. COX6b2 is specifically expressed in testis and is found to be upregulated in certain cancer cell lines.

Specification
Aliases	CT59; COXVIB2
Entrez GeneID	125965;
Swissprot	Q6YFQ2
WB Predicted band size	11kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein corresponding to residues near the N terminal of human cytochrome c oxidase subunit VIb polypeptide 2 (testis)
Formulation	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Application
WB	1/500-1/2000
IHC	1/50-1/200

	Gel: 10%SDS-PAGE Lysate: 40ug A549 cell Primary antibody: 1/500 dilution Secondary antibody dilution: 1/8000 Exposure time: 5 seconds
	Immunohistochemical analysis of paraffin-embedded Human brain tissue using P42763 at dilution 1/50.