Rabbit Polyclonal Antibody to CRFR1 (Q103)

包装: 1G|100G|500G|1KG|100KG

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别名:Corticotropin-releasing factor receptor 1, CRF-R-1, CRF-R1, CRFR-1, Corticotropin-releasing hormone receptor 1, CRH-R-1, CRH-R1, CRHR1, CRFR, CRFR1, CRHR
应用:WB,FCM
反应种属:Human, Rat
规格：50μl/100μl

Description
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants.

Description

This gene encodes a G-protein coupled receptor that binds
neuropeptides of the corticotropin releasing hormone family that
are major regulators of the hypothalamic-pituitary-adrenal pathway.
The encoded protein is essential for the activation of signal
transduction pathways that regulate diverse physiological processes
including stress, reproduction, immune response and obesity.
Alternative splicing results in multiple transcript variants.

Specification
Aliases	Corticotropin-releasing factor receptor 1, CRF-R-1, CRF-R1, CRFR-1, Corticotropin-releasing hormone receptor 1, CRH-R-1, CRH-R1, CRHR1, CRFR, CRFR1, CRHR
Entrez GeneID	104909134;1394
Swissprot	P34998
WB Predicted band size	50.7kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Rat
Immunogen	This CRFR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-119 amino acids from human CRFR1.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
FCM	1/10-1/50

	CRFR1 Antibody (Q103) (Cat. #P30959) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CRFR1 antibody detected the CRFR1 protein (arrow).
	CRFR1 Antibody (Q103) (Cat. #P30959) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.