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Rabbit Polyclonal Antibody to CRMP-2 (Ab-509)

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别名:Collapsin response mediator protein 2; CRMP2; Dihydropyrimidinase related protein-2; DPYL2; DPYSL2
应用:WB,IHC
反应种属:Human
规格:50μl/100μl

Description
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.Goshima Y., Nature 376:509-514(1995).Hamajima N., Gene 180:157-163(1996).Kitamura K., DNA Res. 6:291-297(1999).
Specification
Aliases Collapsin response mediator protein 2; CRMP2; Dihydropyrimidinase related protein-2; DPYL2; DPYSL2
Entrez GeneID 1808;
Swissprot Q16555
WB Predicted band size 50kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized non-phosphopeptide derived from human CRMP-2 around the phosphorylation site of threonine 509 (S-V-T(p)-P-K).
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application
WB 1/500-1/3000
IHC 1/50-1/100

Western blot analysis of extracts from HT-29 cells, treated with heat shock, using CRMP-2 (Ab-509) antibody P41751.
Western blot analysis of extracts from COS7 cells (Lane 2), using CRMP-2 (Ab-509) antiobdy P41751. The lane on the left is treated with systhesized peptide.
Immunohistochemistry analysis of paraffin-embedded human brain tissue using CRMP-2 (Ab-509) antibody P41751.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。