别名:CRMP2; N2A3; TOAD-64; DPYL2; ULIP2应用:WB,IHC
反应种属:Human,Mouse,Rat
规格:50μl/100μl
Description |
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CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain. Miki Y., Science 266:66-71(1994)Smith T.M., Genome Res. 6:1029-1049(1996)Wilson C.A., Oncogene 14:1-16(1997) |
Specification | |
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Aliases | CRMP2; N2A3; TOAD-64; DPYL2; ULIP2 |
Entrez GeneID | 1808; |
Swissprot | Q16555 |
WB Predicted band size | 50kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Peptide sequence around phosphorylation site of threonine 509 (S-V-T(p)-P-K) derived from Human CRMP-2. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/1000 |
IHC | 1/50-1/100 |
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Western blot analysis of extracts from HT-29 cells treated with heat shock using CRMP-2 (Phospho-Thr509) Antibody P40495.The lane on the right is treated with the antigen-specific peptide. |
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Immunohistochemical analysis of paraffin-embedded human brain tissue using CRMP-2 (Phospho-Thr509) antibody P40495 (left)or the same antibody preincubated with blocking peptide (right). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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