库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to CRYGD

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别名:Gamma-crystallin D, Gamma-D-crystallin, Gamma-crystallin 4, CRYGD, CRYG4
应用:WB
反应种属:Human
规格:50μl/100μl

Description
Crystallins are separated into two classes:
taxon-specific, or enzyme, and ubiquitous. The latter class
constitutes the major proteins of vertebrate eye lens and maintains
the transparency and refractive index of the lens. Since lens
central fiber cells lose their nuclei during development, these
crystallins are made and then retained throughout life, making them
extremely stable proteins. Mammalian lens crystallins are divided
into alpha, beta, and gamma families; beta and gamma crystallins
are also considered as a superfamily. Alpha and beta families are
further divided into acidic and basic groups. Seven protein regions
exist in crystallins: four homologous motifs, a connecting peptide,
and N- and C-terminal extensions. Gamma-crystallins are a
homogeneous group of highly symmetrical, monomeric proteins
typically lacking connecting peptides and terminal extensions. They
are differentially regulated after early development. Four
gamma-crystallin genes (gamma-A through gamma-D) and three
pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a
genomic segment as a gene cluster. Whether due to aging or
mutations in specific genes, gamma-crystallins have been involved
in cataract formation.
Specification
Aliases Gamma-crystallin D, Gamma-D-crystallin, Gamma-crystallin 4, CRYGD, CRYG4
Entrez GeneID 1421
Swissprot P07320
WB Predicted band size 20.7kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This CRYGD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-101 amino acids from the Central region of human CRYGD.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

CRYGD Antibody (Center)(Cat. #P32052) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CRYGD antibody detected the CRYGD protein (arrow).

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。