Rabbit Polyclonal Antibody to CSF2

包装: 1G|100G|500G|1KG|100KG

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别名:Granulocyte-macrophage colony-stimulating factor, GM-CSF, Colony-stimulating factor, CSF, Molgramostin, Sargramostim, CSF2, GMCSF
应用:WB,IHC,ICC,FCM
反应种属:Human
规格：50μl/100μl

Description
CSF2 is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq].

Description

CSF2 is a cytokine that
controls the production, differentiation, and function of
granulocytes and macrophages. The active form of the protein is
found extracellularly as a homodimer. This gene has been localized
to a cluster of related genes at chromosome region 5q31, which is
known to be associated with interstitial deletions in the 5q-
syndrome and acute myelogenous leukemia. Other genes in the cluster
include those encoding interleukins 4, 5, and 13. [provided by
RefSeq].

Specification
Aliases	Granulocyte-macrophage colony-stimulating factor, GM-CSF, Colony-stimulating factor, CSF, Molgramostin, Sargramostim, CSF2, GMCSF
Entrez GeneID	1437
Swissprot	P04141
WB Predicted band size	16.3kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This CSF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-85 amino acids from the Central region of human CSF2.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500
ICC	1/10-1/50
FCM	1/10-1/50

	CSF2 Antibody (Center) (Cat. #P30830) western blot analysis in HL60 cell line lysates (35ug/lane).This demonstrates the CSF2 antibody detected the CSF2 protein (arrow).
	Confocal immunofluorescent analysis of CSF2 Antibody (Center) (Cat#P30830) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
	CSF2 Antibody (Center) (Cat. #P30830) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
	CSF2 antibody (Center) (Cat. #P30830) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CSF2 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.