Rabbit Polyclonal Antibody to CUTL1

包装: 1G|100G|500G|1KG|100KG

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别名:CCAAT displacement protein; CDP; Cut-like 1;
应用:WB
反应种属:Human,Mouse
规格：50μl/100μl

Description
Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5′ and 3′) of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator By similarity.Neufeld E.J., Nat. Genet. 1:50-55(1992).Gloeckner G., Genome Res. 8:1060-1073(1998).Rong Zeng W., Gene 241:75-85(2000).

Description

Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5′ and 3′) of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator By similarity.Neufeld E.J., Nat. Genet. 1:50-55(1992).Gloeckner G., Genome Res. 8:1060-1073(1998).Rong Zeng W., Gene 241:75-85(2000).

Specification
Aliases	CCAAT displacement protein; CDP; Cut-like 1;
Entrez GeneID	1523;
Swissprot	Q13948
WB Predicted band size	164kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from N-terminal of human CUTL1.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.