中文 
别名:BCL-1 ; oncogene; CYL-1; PRAD1; PRAD1应用:WB
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes ‘Lys-48’-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.Liou YC, et al. (2002) Proc Natl Acad Sci U S A 99, 1335-40 Tagliati F, et al. (2006) Endocrinology 147, 3530-8Zou Y, et al. (2004) J Biol Chem 279, 27790-8 |
| Specification | |
|---|---|
| Aliases | BCL-1 ; oncogene; CYL-1; PRAD1; PRAD1 |
| Entrez GeneID | 595; |
| Swissprot | P24385 |
| WB Predicted band size | 33kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of threonine 286 (A-C-T(p)-P-T) derived from Human Cyclin D1. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
 |
Western blot analysis of extracts from MCF7 tissue using Cyclin D1 (Phospho-Thr286) antibody P40602.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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