别名:CCND1; BCL1; D11S287E; PRAD1; U21B31; Cyclin D1应用:WB,IHC,IP
反应种属:Human,Mouse,Rat
规格:50μl/100μl
| Description |
|---|
| Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. |
| Specification | |
|---|---|
| Aliases | CCND1; BCL1; D11S287E; PRAD1; U21B31; Cyclin D1 |
| Entrez GeneID | 595 |
| Swissprot | P24385 |
| WB Predicted band size | Calculated MW: 34 kDa; Observed MW: 34 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthetic peptide of human Cyclin D1 |
| Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Application | |
|---|---|
| IP | 1/20 |
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
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Western blot analysis of Cyclin D1 in 3T3 lysates using Cyclin D1 antibody. |
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Western blot analysis of Cyclin D1 in MCF-7, C6, PC-12 lysates using Cyclin D1 antibody. |
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Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Cyclin D1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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