库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to CYP1A1

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别名:AHH; AHRR; CP11; CYP1; P1-450; P450-C; P450DX
应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl

Description
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme’s endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
Specification
Aliases AHH; AHRR; CP11; CYP1; P1-450; P450-C; P450DX
Swissprot P04798
WB Predicted band size 58 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Synthetic peptide of human CYP1A1
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
WB 1/200-1/1000
ELISA 1/1000-1/2000

Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Mouse lung tissue, Primary antibody: P12015(CYP1A1 Antibody) at dilution 1/220, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。