别名:CP7A; CYP7; CYPVII应用:IHC
反应种属:Human
规格:50μl/100μl
Description |
---|
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. |
Specification | |
---|---|
Aliases | CP7A; CYP7; CYPVII |
Entrez GeneID | 1581; |
Swissprot | P22680 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human cytochrome P450, family 7, subfamily A, polypeptide 1 |
Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Application | |
---|---|
IHC | 1/25-1/100 |
![]() |
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using P42941 at dilution 1/20. |
![]() |
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using P42941 at dilution 1/20. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
暂无评论
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
发表回复