Rabbit Polyclonal Antibody to Cytochrome P452A6

包装: 1G|100G|500G|1KG|100KG

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别名:Cytochrome P450 2A6; EC 1.14.14.1; CYPIIA6; Coumarin 7-hydroxylase; P450 IIA3
应用:WB
反应种属:Human
规格：50μl/100μl

Description
Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.Miles J.S., ic Acids Res. 17:2907-2917(1989).Yamano S., Biochemistry 29:1322-1329(1990).Saito S., J. Hum. Genet. 48:249-270(2003).

Description

Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.Miles J.S., ic Acids Res. 17:2907-2917(1989).Yamano S., Biochemistry 29:1322-1329(1990).Saito S., J. Hum. Genet. 48:249-270(2003).

Specification
Aliases	Cytochrome P450 2A6; EC 1.14.14.1; CYPIIA6; Coumarin 7-hydroxylase; P450 IIA3
Entrez GeneID	1548;
Swissprot	P11509
WB Predicted band size	56kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from N-terminal of human Cytochrome P450 2A6.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.