Rabbit Polyclonal Antibody to Cytochrome P452C8

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

400-880-2824

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:Cytochrome P450 2C8; EC 1.14.14.1; CYPIIC8; P450 form 1; P450 MP-12/MP-20
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol).Romkes M., Biochemistry 30:3247-3255(1991).Ged C., Biochim. Biophys. Acta 1088:433-435(1991).Zeldin D.C., Arch. Biochem. Biophys. 322:76-86(1995).

Description

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol).Romkes M., Biochemistry 30:3247-3255(1991).Ged C., Biochim. Biophys. Acta 1088:433-435(1991).Zeldin D.C., Arch. Biochem. Biophys. 322:76-86(1995).

Specification
Aliases	Cytochrome P450 2C8; EC 1.14.14.1; CYPIIC8; P450 form 1; P450 MP-12/MP-20
Entrez GeneID	1558;
Swissprot	P10632
WB Predicted band size	56kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from internal of human Cytochrome P450 2C8.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100

	Western blot analysis of extracts from HuvEc cells, using Cytochrome P450 2C8 antiobdy P42192.
	Immunohistochemistry analysis of paraffin-embedded human testis tissue, using Cytochrome P450 2C8 antibody P42192.