别名:Mitogen-activated protein kinase 12, MAP kinase 12, MAPK 12, Stress-activated protein kinase 3, mapk12, sapk3应用:WB
反应种属:zebrafish
规格:50μl/100μl
| Description |
|---|
| Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK12 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases such as MAPKAPK2, which are activated through phosphorylation and further phosphorylate additional targets (By similarity). |
| Specification | |
|---|---|
| Aliases | Mitogen-activated protein kinase 12, MAP kinase 12, MAPK 12, Stress-activated protein kinase 3, mapk12, sapk3 |
| Swissprot | O42376 |
| WB Predicted band size | 42.0kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | zebrafish |
| Immunogen | This (DANRE) mapk12 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 319-353 amino acids of DANRE mapk12. |
| Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Application | |
|---|---|
| WB | 1/1000 |
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Western blot analysis of lysates from zebra fish brain, Zebrafish tissue lysate (from left to right), using (DANRE) mapk12 Antibody (C-term)(Cat. #P32760). P32760 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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