中文 
别名:Protein DJ-1, zDJ-1, 34–, Parkinson disease protein 7 homolog, park7 {ECO:0000312|EMBL:AAH834751}应用:WB
反应种属:zebrafish, Mouse, Rat
规格：50μl/100μl
| Description |
|---|
| Protects cells against oxidative stress and cell death. May act as an atypical peroxiredoxin-like peroxidase that scavenges hydrogen peroxide. Following removal of a C-terminal peptide, displays protease activity and enhanced cytoprotective action against oxidative stress-induced apoptosis. Binds to a number of mRNAs containing multiple copies of GG or CC motifs and partially inhibits their translation but dissociates following oxidative stress. Required for correct mitochondrial morphology and function and for autophagy of dysfunctional mitochondria. Regulates astrocyte inflammatory responses. Acts as a positive regulator of androgen receptor-dependent transcription. Prevents aggregation of SNCA. Plays a role in fertilization. Has no proteolytic activity. Has cell-growth promoting activity and transforming activity. May function as a redox-sensitive chaperone (By similarity). Protects dopaminergic neurons against cell death arising from oxidative stress and proteasome inhibition, probably by a TP53/p53-dependent mechanism. |
| Specification | |
|---|---|
| Aliases | Protein DJ-1, zDJ-1, 34–, Parkinson disease protein 7 homolog, park7 {ECO:0000312|EMBL:AAH834751} |
| Entrez GeneID | 449674 |
| Swissprot | Q5XJ36 |
| WB Predicted band size | 19.8kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | zebrafish, Mouse, Rat |
| Immunogen | This DANRE park7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-149 amino acids from the C-terminal region of DANRE park7. |
| Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Application | |
|---|---|
| WB | 1/1000 |
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DANRE park7 Antibody (C-term) (Cat. #P32530) western blot analysis in zebra fish brain and muscle tissue lysates (35ug/lane).This demonstrates the DANRE park7 antibody detected the DANRE park7 protein (arrow). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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