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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to DAZ2

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别名:Deleted in azoospermia protein 2, DAZ2
应用:WB
反应种属:Human
规格:50μl/100μl

Description
This gene is a member of the DAZ gene family and is a
candidate for the human Y-chromosomal azoospermia factor (AZF). Its
expression is restricted to premeiotic germ cells, particularly in
spermatogonia. It encodes an RNA-binding protein that is important
for spermatogenesis. Four copies of this gene are found on
chromosome Y within palindromic duplications; one pair of genes is
part of the P2 palindrome and the second pair is part of the P1
palindrome. Each gene contains a 2.4 kb repeat including a 72-bp
exon, called the DAZ repeat; the number of DAZ repeats is variable
and there are several variations in the sequence of the DAZ repeat.
Each copy of the gene also contains a 10.8 kb region that may be
amplified; this region includes five exons that encode an RNA
recognition motif (RRM) domain. This gene contains one copy of the
10.8 kb repeat. Alternative splicing results in multiple transcript
variants encoding different isoforms.
Specification
Aliases Deleted in azoospermia protein 2, DAZ2
Entrez GeneID 57055
Swissprot Q13117
WB Predicted band size 63.1kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This DAZ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-546 amino acids from the C-terminal region of human DAZ2.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

DAZ2 Antibody (C-term) (Cat. #P31063) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the DAZ2 antibody detected the DAZ2 protein (arrow).

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。