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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to DAZ4

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别名:pDP1680; pDP1681
应用:WB
反应种属:Human, Mouse
规格:50μl/100μl

Description
This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains two copies of the 10.8 kb repeat. Alternatively spliced transcript variants encoding different isoforms have been described.
Specification
Aliases pDP1680; pDP1681
Swissprot Q86SG3
WB Predicted band size 65 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Fusion protein of human DAZ4
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
WB 1/1000-1/5000
ELISA 1/5000-1/10000

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: HepG2 cell, Mouse stomach tissue, TM4 cell lysates, Primary antibody: P13827(DAZ4 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 5 minutes

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。