别名:E2; E2B; BCATE2; BCKADE2; BCKAD-E2; BCOADC-E2应用:WB,IHC
反应种属:Human, Mouse
规格:50μl/100μl
Description |
---|
The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. |
Specification | |
---|---|
Aliases | E2; E2B; BCATE2; BCKADE2; BCKAD-E2; BCOADC-E2 |
Swissprot | P11182 |
WB Predicted band size | 53 kDa |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human DBT |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Application | |
---|---|
WB | 1/200-1/1000 |
IHC | 1/10-1/50 |
ELISA | 1/5000-1/10000 |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue lysate, Primary antibody: P06355(DBT Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds | |
The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P06355(DBT Antibody) at dilution 1/20. (Original magnification: ×200) |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
暂无评论
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
发表回复