Rabbit Polyclonal Antibody to DEGS1

包装: 1G|100G|500G|1KG|100KG

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别名:MLD; DEGS; DES1; Des-1; FADS7; MIG15; DEGS-1
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.

Description

This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.

Specification
Aliases	MLD; DEGS; DES1; Des-1; FADS7; MIG15; DEGS-1
Swissprot	O15121
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide of human DEGS1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/25-1/100
ELISA	1/5000-1/10000

	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P13246(DEGS1 Antibody) at dilution 1/20. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P13246(DEGS1 Antibody) at dilution 1/20. (Original magnification: ×200)