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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to DENND1A

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别名:FAM31A; KIAA1608
应用:IHC
反应种属:Human
规格:50μl/100μl

Description
Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).
Specification
Aliases FAM31A; KIAA1608
Swissprot Q8TEH3
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Fusion protein of human DENND1A
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
IHC 1/50-1/200
ELISA 1/5000-1/10000

The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P09618(DENND1A Antibody) at dilution 1/50. (Original magnification: ×200)

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。