Rabbit Polyclonal Antibody to DGKH

包装: 1G|100G|500G|1KG|100KG

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别名:iacylglycerol kinase eta; EC 2.7.1.107; Diglyceride kinase eta; DGK-eta; DAG kinase eta
应用:IHC,ICC
反应种属:Human
规格：50μl/100μl

Description
Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization.Murakami T., J. Biol. Chem. 278:34364-34372(2003) .Dunham A., Nature 428:522-528(2004). Ota T., Nat. Genet. 36:40-45(2004).

Description

Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization.Murakami T., J. Biol. Chem. 278:34364-34372(2003) .Dunham A., Nature 428:522-528(2004). Ota T., Nat. Genet. 36:40-45(2004).

Specification
Aliases	iacylglycerol kinase eta; EC 2.7.1.107; Diglyceride kinase eta; DGK-eta; DAG kinase eta
Entrez GeneID	160851;
Swissprot	Q86XP1
WB Predicted band size	135kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from internal of human DGKH.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
IHC	1/50-1/100
ICC	1/100-1/500

	Immunofluorescence analysis of HeLa cells, using DGKH antibody P42035.
	Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using DGKH antibody P42035.