别名:Type I iodothyronine deiodinase, 5DI, DIOI, Type 1 DI, Type-I 5′-deiodinase, DIO1, ITDI1, TXDI1应用:WB
反应种属:Human
规格:50μl/100μl
Description |
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DIO1 is a thiol-requiring propylthiouracil-sensitive oxidoreductase. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3′,5-triiodothyronine (T3). It also degrades both hormones by inner ring deiodination (IRD). |
Specification | |
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Aliases | Type I iodothyronine deiodinase, 5DI, DIOI, Type 1 DI, Type-I 5′-deiodinase, DIO1, ITDI1, TXDI1 |
Entrez GeneID | 1733 |
Swissprot | P49895 |
WB Predicted band size | 28.9kDa |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This DIO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-57 amino acids from the N-terminal region of human DIO1. |
Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Application | |
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WB | 1/1000 |
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Anti-DIO1 Antibody (N-term) at 1:2000 dilution + human kidney whole cell lysate
Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 29 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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