Rabbit Polyclonal Antibody to DLC1 (Phospho-Ser986)

包装: 1G|100G|500G|1KG|100KG

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别名:ARHGAP7, KIAA1723, STARD12
应用:WB
反应种属:Human
规格：50μl/100μl

Description
Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.

Description

Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.

Specification
Aliases	ARHGAP7, KIAA1723, STARD12
Entrez GeneID	10395;
Swissprot	Q96QB1
WB Predicted band size	171kDa 114kDa 123kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of serine 986 (R-D-S(p)-G-V) derived from Human DLC1.
Formulation	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.