别名:ARHGAP7; KIAA1723; STARD12; Rho GTPase-activating protein 7应用:WB
反应种属:Human
规格:50μl/100μl
| Description |
|---|
| Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality. |
| Specification | |
|---|---|
| Aliases | ARHGAP7; KIAA1723; STARD12; Rho GTPase-activating protein 7 |
| Entrez GeneID | 10395 |
| Swissprot | Q96QB1 |
| WB Predicted band size | Calculated MW: 171 kDa; Observed MW: 171,127,123,114 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide of human DLC1 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
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Western blot analysis of DLC1 in 293T, DU145, SKOV-3, HT-29 lysates using DLC1 antibody. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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