Rabbit Polyclonal Antibody to DLL4

包装: 1G|100G|500G|1KG|100KG

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别名:Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4
应用:WB
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.

Description

Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.

Specification
Aliases	Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4
Entrez GeneID	54567
Swissprot	Q9NR61
WB Predicted band size	74.6kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	This DLL4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 608-641 amino acids from human DLL4.