Rabbit Polyclonal Antibody to DLX5

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

400-880-2824

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:Homeobox protein DLX-5; DLX5;
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5′-TAATTA-3′ consensus sequence for DNA-binding.Ota T., Nat. Genet. 36:40-45(2004).Hillier L.W., Nature 424:157-164(2003).Willis D.M., J. Biol. Chem. 277:37280-37291(2002).

Description

Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5′-TAATTA-3′ consensus sequence for DNA-binding.Ota T., Nat. Genet. 36:40-45(2004).Hillier L.W., Nature 424:157-164(2003).Willis D.M., J. Biol. Chem. 277:37280-37291(2002).

Specification
Aliases	Homeobox protein DLX-5; DLX5;
Entrez GeneID	1749;
Swissprot	P56178
WB Predicted band size	32kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthesized peptide derived from internal of human DLX5.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100

	Western blot analysis of extracts from HeLa cells, 293 cells and COLO205 cells, using DLX5 antibody P41971.
	Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using DLX5 antibody P41971.