Rabbit Polyclonal Antibody to DNAJB6

包装: 1G|100G|500G|1KG|100KG

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别名:DnaJ homolog subfamily B member 6, HHDJ1, Heat shock protein J2, HSJ-2, MRJ, MSJ-1, DNAJB6, HSJ2, MRJ, MSJ1
应用:WB,IHC,FCM
反应种属:Human
规格：50μl/100μl

Description
This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the ‘J-domain’ and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.

Description

This gene encodes a member of the DNAJ protein family.
DNAJ family members are characterized by a highly conserved amino
acid stretch called the ‘J-domain’ and function as one of the two
major classes of molecular chaperones involved in a wide range of
cellular events, such as protein folding and oligomeric protein
complex assembly. This family member may also play a role in
polyglutamine aggregation in specific neurons. Alternative splicing
of this gene results in multiple transcript variants; however, not
all variants have been fully described.

Specification
Aliases	DnaJ homolog subfamily B member 6, HHDJ1, Heat shock protein J2, HSJ-2, MRJ, MSJ-1, DNAJB6, HSJ2, MRJ, MSJ1
Entrez GeneID	10049
Swissprot	O75190
WB Predicted band size	36.1kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This DNAJB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-247 amino acids from the Central region of human DNAJB6.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500
FCM	1/10-1/50

	Western blot analysis of DNAJB6 Antibody (Center) Pab (Cat. #P31097) pre-incubated without(lane 1) and with(lane 2) blocking peptide in Hela cell line lysate. DNAJB6 Antibody (Center) (arrow) was detected using the purified Pab.
	DNAJB6 Antibody (Center) (Cat. #P31097) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
	DNAJB6 Antibody (Center) (Cat. #P31097)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DNAJB6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.