库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to DOCK11

现货 支持定制

  • 满200元免运费
  • 正品保障 提供发票
  • 现货闪电 当时发货

别名:ACG; ZIZ2; bB128O4.1
应用:IHC
反应种属:Human, Mouse
规格:50μl/100μl

Description
Small GTPases of the Rho family, Rho, Rac, and Cdc42, are critical regulators of the actin cytoskeleton and many other cellular processes. Rho GTPases are activated by Dbl-homology (DH)-domain-containing guanine nucleotide exchange factors (GEFs). DOCK 11 (dedicator of cytokinesis 11), also known as ACG or ZIZ2 (zizimin2), is a 2073 amino acid protein belonging to the DOCK family of cytokinesis-regulating proteins that is mainly expressed in peripheral blood leukocytes. DOCK 11 functions as a GEF that binds and activates Cdc42 by exchanging bound GDP for free GTP. Cdc42 mediates cell polarity, gene expression, cell cycle progression and cell–cell contacts. Similar to other DOCK family members, DOCK 11 contains a PH domain and two internal DOCK homology regions designated DHR1 and DHR2.
Specification
Aliases ACG; ZIZ2; bB128O4.1
Swissprot Q5JSL3
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse
Immunogen Synthetic peptide of human DOCK11
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
IHC 1/20-1/100
ELISA 1/5000-1/10000

The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P06394(DOCK11 Antibody) at dilution 1/35. (Original magnification: ×200)
The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P06394(DOCK11 Antibody) at dilution 1/35. (Original magnification: ×200)

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

暂无评论

发表回复

您的邮箱地址不会被公开。 必填项已用 * 标注


本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。