Rabbit Polyclonal Antibody to DOK4

包装: 1G|100G|500G|1KG|100KG

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别名:Docking protein 4; Downstream of tyrosine kinase 4; DOK4;
应用:WB
反应种属:Human,Mouse
规格：50μl/100μl

Description
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway By similarity. Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.Favre C., Genes Immun. 4:40-45(2003).Cai D., J. Biol. Chem. 278:25323-25330(2003).Loftus B.J., Genomics 60:295-308(1999).

Description

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway By similarity. Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.Favre C., Genes Immun. 4:40-45(2003).Cai D., J. Biol. Chem. 278:25323-25330(2003).Loftus B.J., Genomics 60:295-308(1999).

Specification
Aliases	Docking protein 4; Downstream of tyrosine kinase 4; DOK4;
Entrez GeneID	55715;
Swissprot	Q8TEW6
WB Predicted band size	37kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from internal of human DOK4.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.