Rabbit Polyclonal Antibody to DOK5

包装: 1G|100G|500G|1KG|100KG

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别名:Docking protein 5; Downstream of tyrosine kinase 5; Insulin receptor substrate 6; IRS-6; IRS6
应用:WB
反应种属:Human
规格：50μl/100μl

Description
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.Luo W.Q., Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.Favre C., Genes Immun. 4:40-45(2003).Cai D., J. Biol. Chem. 278:25323-25330(2003).

Description

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.Luo W.Q., Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.Favre C., Genes Immun. 4:40-45(2003).Cai D., J. Biol. Chem. 278:25323-25330(2003).

Specification
Aliases	Docking protein 5; Downstream of tyrosine kinase 5; Insulin receptor substrate 6; IRS-6; IRS6
Entrez GeneID	55816;
Swissprot	Q9P104
WB Predicted band size	36kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from internal of human DOK5.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.