Rabbit Polyclonal Antibody to DPYSL2

包装: 1G|100G|500G|1KG|100KG

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别名:DRP2, N2A3, CRMP2, DRP-2, ULIP2, CRMP-2, DHPRP2, ULIP-2
应用:WB,IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer’s disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Description

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer’s disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specification
Aliases	DRP2, N2A3, CRMP2, DRP-2, ULIP2, CRMP-2, DHPRP2, ULIP-2
Swissprot	Q16555
WB Predicted band size	62 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide of human DPYSL2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/200-1/1000
IHC	1/25-1/100
ELISA	1/1000-1/5000

	Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane: NIH/3T3 cells, Primary antibody: P03834(DPYSL2 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds
	The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P03834(DPYSL2 Antibody) at dilution 1/45. (Original magnification: ×200)