Rabbit Polyclonal Antibody to DR6 (phospho-Ser562)

包装: 1G|100G|500G|1KG|100KG

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别名:Tumor necrosis factor receptor superfamily member 21 (Death receptor 6) (CD antigen CD358)
应用:WB
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
TNF receptor superfamily member 21(TNFRSF21) Homo sapiens This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013],

Description

TNF receptor superfamily member 21(TNFRSF21) Homo sapiens This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013],

Specification
Aliases	Tumor necrosis factor receptor superfamily member 21 (Death receptor 6) (CD antigen CD358)
Entrez GeneID	27242
Swissprot	O75509
WB Predicted band size	72kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthesized phosho peptide around human DR6 (Ser562)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.