Rabbit Polyclonal Antibody to DTYMK

包装: 1G|100G|500G|1KG|100KG

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别名:CDC8; TMPK; TYMK; PP3731
应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
DTYMK (deoxythymidylate kinase (thymidylate kinase)), also known as CDC8, TMPK, TYMK or dTMP kinase, is a 212 amino acid protein that belongs to the thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. DTYMK expression levels peak during the S phase (synthesis phase) of the cell cycle, further supporting the role of DTYMK in DNA synthesis.

Description

DTYMK (deoxythymidylate kinase (thymidylate kinase)), also known as CDC8, TMPK, TYMK or dTMP kinase, is a 212 amino acid protein that belongs to the thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. DTYMK expression levels peak during the S phase (synthesis phase) of the cell cycle, further supporting the role of DTYMK in DNA synthesis.

Specification
Aliases	CDC8; TMPK; TYMK; PP3731
Swissprot	P23919
WB Predicted band size	24 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human DTYMK
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/50-1/300
ELISA	1/5000-1/10000

	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-6: Raji, K562, Hela, HepG2, 293T cell and Human fetal liver tissue lysates, Primary antibody: P02858(DTYMK Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
	The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P02858(DTYMK Antibody) at dilution 1/70. (Original magnification: ×200)