中文 
别名:PAC1; PAC-1应用:WB,IHC
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. |
| Specification | |
|---|---|
| Aliases | PAC1; PAC-1 |
| Entrez GeneID | 1844; |
| Swissprot | Q05923 |
| WB Predicted band size | 34kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthetic peptide corresponding to residues near the C terminal of human dual specificity phosphatase 2 |
| Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
| Application | |
|---|---|
| WB | 1/200-1/1000 |
| IHC | 1/25-1/100 |
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Gel: 8%SDS-PAGE Lysate: 40ug Hela cell Primary antibody: 1/300 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute |
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Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using P42923 at dilution 1/30. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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