Rabbit Polyclonal Antibody to DUSP27

包装: 1G|100G|500G|1KG|100KG

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别名:
应用:IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members, including MAPK/ERK, SAPK/JNK and p38. DUSP27 (dual specificity phosphatase 27), also known as FMDSP or DUPD1 (dual specificity phosphatase and pro isomerase domain containing 1), is a 220 amino acid cytoplasmic protein that belongs to the protein-tyrosine phosphatase family. Expressed in skeletal muscle, liver and adipose tissue, DUSP27 may play a role in energy metabolism. The gene encoding DUSP27 is referred to as DUPD1 and maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.

Description

Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members, including MAPK/ERK, SAPK/JNK and p38. DUSP27 (dual specificity phosphatase 27), also known as FMDSP or DUPD1 (dual specificity phosphatase and pro isomerase domain containing 1), is a 220 amino acid cytoplasmic protein that belongs to the protein-tyrosine phosphatase family. Expressed in skeletal muscle, liver and adipose tissue, DUSP27 may play a role in energy metabolism. The gene encoding DUSP27 is referred to as DUPD1 and maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.

Specification
Swissprot	Q5VZP5
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Synthetic peptide of human DUSP27
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/50-1/300
ELISA	1/5000-1/10000

	The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P06403(DUSP27 Antibody) at dilution 1/50. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P06403(DUSP27 Antibody) at dilution 1/50. (Original magnification: ×200)