Rabbit Polyclonal Antibody to DVL1

包装: 1G|100G|500G|1KG|100KG

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别名:DVL; DRS2; DVL1L1; DVL1P1
应用:IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.

Description

DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.

Specification
Aliases	DVL; DRS2; DVL1L1; DVL1P1
Swissprot	O14640
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide of human DVL1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/20-1/100
ELISA	1/2000-1/5000

	The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P12510(DVL1 Antibody) at dilution 1/20. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P12510(DVL1 Antibody) at dilution 1/20. (Original magnification: ×200)