Rabbit Polyclonal Antibody to Dysferlin

包装: 1G|100G|500G|1KG|100KG

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别名:dysferlin; limb girdle muscular dystrophy 2B (autosomal recessive);
应用:WB
反应种属:Human,Mouse
规格：50μl/100μl

Description
Key calcium ion sensor involved in the Ca2+-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress By similarity.Delia J. Hern篓垄ndez-Deviez, Hum. Mol. Genet., Jan 2006; 15: 129 – 142. Yanchao Huang, FASEB J, Mar 2007; 21: 732 – 742.Mengfatt Ho, Hum. Mol. Genet., Sep 2004; 13: 1999 – 2010.Eriko Fujita, Hum. Mol. Genet., Mar 2007; 16: 618 – 629.

Description

Key calcium ion sensor involved in the Ca2+-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress By similarity.Delia J. Hern篓垄ndez-Deviez, Hum. Mol. Genet., Jan 2006; 15: 129 – 142. Yanchao Huang, FASEB J, Mar 2007; 21: 732 – 742.Mengfatt Ho, Hum. Mol. Genet., Sep 2004; 13: 1999 – 2010.Eriko Fujita, Hum. Mol. Genet., Mar 2007; 16: 618 – 629.

Specification
Aliases	dysferlin; limb girdle muscular dystrophy 2B (autosomal recessive);
Entrez GeneID	8291;
Swissprot	O75923
WB Predicted band size	240kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from human Dysferlin.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000

	Western blot analysis of extracts from K562 cells, using Dysferlin antibody P41797.
	Western blot analysis of extracts from JK cells (Lane 2) and K562 cells (Lane 3), using Dysferlin antiobdy P41797. The lane on the left is treated with synthesized peptide.