中文 
别名:E12; Tran; TCF3; TFE2; ITF1应用:IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl
| Description |
|---|
| E2A is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5′- CANNTG-3′. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described. Kamps M.P., Cell 60:547-555(1990)Nourse J., Cell 60:535-545(1990)Grimwood J., Nature 428:529-535(2004) |
| Specification | |
|---|---|
| Aliases | E12; Tran; TCF3; TFE2; ITF1 |
| Entrez GeneID | 6929; |
| Swissprot | P15923 |
| WB Predicted band size | 67kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around phosphorylation site of threonine 355 (P-S-T(p)-P-V) derived from Human E2A . |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| IHC | 1/50-1/100 |
 |
Immunohistochemical analysis of paraffin-embedded human brain tissue using E2A (Phospho-Thr355) antibody P40498 (left)or the same antibody preincubated with blocking peptide (right). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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